Blood type and stroke risk: what a large-scale study showed

A large study of 617,000 people found that blood type can affect the risk of early stroke. In addition, people with blood type A (II) have a 16% higher risk of stroke before the age of 60. At the same time, people with type O (I) , on the contrary, have a 12% lower risk .

In a study published in 2022, genomic scientists found a clear link between the subgroup A gene and early-onset stroke. They pooled data from 48 genetic studies involving about 17,000 people with stroke and nearly 600,000 people without stroke. The participants were between the ages of 18 and 59.

An analysis of specific types of blood type genes showed that people with type A have a 16% higher risk of stroke before the age of 60 compared to people with other blood types.

For those with type O (I), the risk is 12% lower.

We still don't know why blood type A increases the risk of stroke. But it's likely related to blood clotting factors, as well as other circulating proteins that play a role in blood clot formation

– said the study's senior author, vascular neurologist Stephen Kittner from the University of Maryland.

Kittner believes that further research is needed to clarify the mechanism of the increased risk of stroke.

Another key finding of the study was obtained by comparing people who had a stroke before the age of 60 with those who had a stroke after the age of 60.

They found that the increased risk of stroke in people with blood type O became insignificant in the late stroke group, suggesting that strokes that occur early in life may have a different mechanism than strokes that occur later in life.

According to the authors, strokes in young people are less likely to be caused by the accumulation of fatty deposits in the arteries (atherosclerosis) and more likely to be caused by factors related to the formation of blood clots.

The study also showed that people with blood type B(III) have about an 11% higher chance of having a stroke.

According to Heathline, regular flossing may reduce the risk of stroke and atrial fibrillation (AFib). People who floss regularly have a 22% lower risk of ischemic stroke and a 44% lower chance of cardioembolic stroke. Researchers suggest that oral care reduces inflammation, which affects the heart and blood vessels.

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